Ceribell Case Study:
NCSE Detected in TBI Patient w/ Remote History of Decompressive Hemicraniectomy

Patient
21 y/o M s/p motorcycle crash. He had multifocal ICH, downward transtentorial herniation, and facial/skull fractures necessitating decompressive hemicraniectomy. Complex hospital course complicated by significant paroxysmal sympathetic hyperreactivity.
Timeline
- On hospital day ~60, patient had a witnessed seizure on neuro floor unit
- GCS 6T
- Neurosurgery and neurocritical care were called to the bedside
- Ceribell applied and immediately recorded >90% seizure burden (neurologist confirmed patient in status)
- 0935 1mg lorazepam
- 0940 4mg lorazepam
- 0945 2mg lorazepam
- Ceribell monitoring continued for several hours with 0% seizure burden
- Patient transferred to ICU for higher-level care and placed on a mechanical vent
Impact
- POC EEG promptly detected NCSE in a patient with recent history of TBI, skull fracture and ICH. Later found to have hydrocephalus
- Real-time monitoring allowed for data-driven medication management using seizure burden
Case study is representative of real medical events.