Clinical Data and Supporting Evidence

Fast. Accurate. Informed.

TREAT PATIENTS WITH PRECISION WHEN SECONDS COUNT IN CRITICAL CARE

The Ceribell Rapid Response EEG system has been clinically demonstrated to empower critical care physicians to make faster, more accurate diagnostic decisions for informed treatment choices.

4 HRS

Wait-time to Conventional EEG Versus 5 Minutes with Ceribell EEG

  • Even in top academic centers with 24/7 on-site EEG technologists
90 %

Diagnostic accuracy with the Ceribell Versus 65% Using Clinical Judgement Alone

  • With Ceribell EEG, sensitivity for detection of seizures was 100% and specificity improved by 25 percentage points..
86 %

Diagnostic Confidence With Ceribell Versus 40% Using Clinical Judgement Alone

  • With Ceribell EEG, bedside clinicians rated their confidence high or very high 86% of the time.

Clarity

Ceribell with Clarity provides consistently high performance that minimizes inter-rater variability53

100%

sensitivity in detecting and alerting for status epilepticus

88%

sensitivity for identifying epileptiform activity

99%

accuracy in ruling out seizure and seizure-like activity

Brain Stethoscope

Ceribell Brain Stethoscopeā„¢ allows highly sensitive spot-checking for detection of seizures

This study compared the sensitivity and specificity of nurses and medical studies for the detection of seizures using Brain Stethoscope versus that of EEG-trained neurologists.

Methods: 69 nurses and medical students used the Brain Stethoscope function to evaluate EEG for seizure activity while 14 neurologists used the visual readout to evaluate the same EEGs.

Results: Nurses and medical students had a higher sensitivity for the detection seizures when using Brain Stethoscope.

Signal Quality

Ceribell electrode signal quality was equivalent to conventional EEG

This study assessed signal quality of the Ceribell Rapid Response EEG system compared to that of two conventional EEG systems to confirm the Ceribell signal quality performance was equivalent to gold standard conventional EEG.

Methods: Ceribell electrodes were placed side-by-side on the same patient with traditional EEG system electrodes and simultaneous recordings were then compared.

Results: The two EEG results showed equivalent signal quality and durability (see overlaid signal below).

10-Electrode Montage

EEG recordings using 10 electrodes meet the gold standard for seizure detection

This study assessed whether reduced montage EEG (rm-EEG) systems, like that used by Ceribell, meet the gold standard full-montage EEG (fm-EEG) for detection of seizures. In the case of discordant diagnoses, it further sought to determine whether the difference was due to electrode reduction or to asymmetric access to ancillary information.

Methods: 212 fm-EEGs were reviewed with access to ancillary information. The same EEGs were converted to rm-EEG (10 electrodes) and different neurologists read them with no ancillary information. EEGs with discordant readings between the two groups were then reviewed again with no access to ancillary information.

Results: The rm-EEG resulted in high diagnostic concordance (95%) with fm-EEG and high agreement between EEG-readers (93%) when ancillary information was equal.